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What is a Nuclear Stress Test?
A nuclear stress test, also known as myocardial perfusion imaging, is a noninvasive test that measures blood flow through the heart, which can also indicate how well the heart is pumping and areas of the heart muscle that are not receiving adequate blood flow.1
The nuclear stress test begins with an injection of a radioactive tracer, a radioactive dye that is absorbed into the heart cells. Once the dye is absorbed, an imaging machine will take pictures of your heart at rest and after exerting yourself.2
Nuclear stress tests use a very low dose of X-rays, but your radiation exposure is quite low and the test is considered safe for most people. Pregnant or nursing mothers should talk to their doctor before having this test, to avoid risk to the baby.3
What is a Nuclear Stress Test Used for?
How Should You Prepare for Your Test?
Before your appointment:
Bring to your appointment:
What Can You Expect During a Nuclear Stress Test?
At the beginning of your appointment, your medical team will confirm your medical history, ask you questions about your exercise habits, and check your heart and lungs.
Before the test begins, a technician will inject the radioactive tracer through an intravenous (IV) line placed in your arm. It may feel chilly when first injected, and will take about 20 - 40 minutes to be absorbed. You’ll be asked to lie flat and still on a table while the clinician takes images of the heart at rest.
The next part of the test is an exercise stress test. Sensors called electrodes will be placed on your chest, legs, and arms, where they will monitor the electrical signals that cause your heartbeats. You’ll have a cuff on your arm to measure your blood pressure, and you may be asked to breathe into a tube. The clinician administering your test will monitor your heartbeats, heart rate and blood pressure while you perform an exercise, usually walking on a treadmill or riding an exercise bike.
When your heart rate peaks or reaches a set rate, you will receive another radioactive tracer. After 20 to 40 minutes to allow it to absorb, more images will be taken of your heart, to see how it functions after exertion.7
What Can You Expect After Your Test?
After the exercise part of your test, you may be asked to stand still for a brief period before lying down. The monitors will remain attached while your heart rate returns to normal. You may need to schedule a follow-up appointment with your doctor to discuss the results.
Unless your doctor tells you otherwise, you should be able to resume your normal routine after the test. Drink plenty of water to help your body will flush the tracer out of your system.8
1,3 American Heart Association, “Myocardial Perfusion Imaging (MPI) Test.” https://www.heart.org/en/health-topics/heart-attack/diagnosing-a-heart-attack/myocardial-perfusion-imaging-mpi-test
2, 4-8 Mayo Clinic, “Nuclear stress test.” https://www.mayoclinic.org/tests-procedures/nuclear-stress-test/about/pac-20385231
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